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main-page >> TCM-Info >> DietTherapy >> Text
Studies Show Preventive Value of Food Supplements

2007-3-17 4:37:04 Viewed: [ Font:Large Medium Small] [ Close]

Common spices and herbs contain ingredients that may prevent the formation of major tumors, such as intestinal and prostate cancers, according to research presented at the American Association for Cancer Research s Second Annual International Conference on Frontiers in Cancer Prevention Research. In particular, recent studies are showing notable cancer prevention potential for the use of ginger extract and a traditional Chinese medicinal herb.

Ginger May Prevent Colorectal Cancer
The ginger family has been used for thousands of years in the treatment and prevention of various illnesses and has been hypothesized to have anti-cancer and therapeutic properties. Ann M. Bode, Ph.D. and Zigang Dong, Ph.D., researchers at the Hormel Institute, University of Minnesota, recently determined that ginger compounds may be effective in preventing and potentially treating colorectal cancer. The theory was tested on human colorectal carcinoma cells (HCT116) in athymic nude mice, that were incapable of rejecting implanted human tumor cells. Prior to tumor cell injection, mice were fed either 500 micrograms of [6]-gingerol (the source of ginger s spiciness) or .001 percent ethanol in water (control) three times per week for two weeks. Following injection, the mice were fed the same ratios. Mice were weighed and tumors were measured by calipers twice each week.


Overall results showed that tumor development was significantly slower in those mice fed [6]-gingerol. The first measurable tumors were observed in both groups on day 15 after injection. However, the control group experienced 13 measurable tumors whereas the [6]-gingerol group reported only four measurable tumors. All mice in the control group developed tumors by day 28, as compared to day 38 for the [6]-gingerol group. Results showed that mice fed [6]-gingerol survived significantly longer than those receiving the control, implying that the tumors grew much slower in the first group. By day 49, all control mice contained tumors at least one cubic centimeter in size. By comparison, 11 mice in the [6]-gingerol group still had not developed tumors of that size.

Preliminary results also suggest that many of the tumors in the control group were invasive into the abdominal cavity, whereas the [6]-gingerol group appeared to be less invasive.
"These results strongly suggest that our hypothesis on the value of ginger is correct," said Dr. Bode, lead author of the study. "As we continue to study the spice in other tumor areas, we hope it will translate into significant anti-cancer properties for humans."
 





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